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A randomised trial comparing argon plasma coagulation (APC) and self-expanding metal stents (SEMS) in oesophageal cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN58821595
Enrollment
Unknown
Registered
2003-09-12
Start date
2002-12-04
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer: oesophageal Cancer Oesophageal

Interventions

Patients not eligible for surgery, presenting with dysphagia (score of >2) will be randomised to primary treatment with either APC or SEMS. Dysphagia management will be as per randomised arm until cli
those with tumour ingrowth would crossover to APC. Quality of life will be quantified using EORTC QLQ-C30 and QLQ-OES, prior to intervention and at 4 weekly intervals. Dysphagia scores will be recorde

Sponsors

Record provided by the NHS Trusts Clinical Trials Register - Department of Health (UK)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with oesophageal cancer who are not eligible for surgery following multi-disciplinary team discussion who are unable to swallow semi-solid food

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

MeasureTime frame
1. Comparison of reductions in dysphagia scores between the two groups 2. Comparison of quality of life scores between the two groups 3. Number of interventions per arm and consequent cost analysis

Secondary

MeasureTime frame
Not provided at time of registration

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026