GnRH antagonist administration for patients at high risk of severe Ovarian Hyperstimulation Syndrome (OHSS) down regulated GnRH agonist

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN58806684

Enrollment

216

Registered

2006-02-28

Start date

2005-11-30

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian Hyperstimulation Syndrome (OHSS) Urological and Genital Diseases Complications associated with artificial fertilization

Interventions

GnRH antagonist versus coasting (care as usual)

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Women undergoing in vitro fertilisation (IVF) or IntraCytoplasmic Sperm Injection (ICSI) trial down regulated with GnRH agonist and at risk of severe OHSS

Exclusion criteria

Exclusion criteria: 1. Women above 39 years old 2. Medical illness

Design outcomes

Primary

Measure	Time frame
Current information as of 24/08/09: High quality embryos Initial information at time of registration: OHSS	—

Secondary

Measure	Time frame
Current information as of 24/08/09: 1. Days of intervention 2. Number of oocytes 3. Pregnancy rate 4. Number of cryopreserved embryos 5. Incidence of severe OHSS Initial information at time of registration: Pregnancy rate	—

Countries

Egypt

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026