Major depressive disorder, generalized anxiety disorder Mental and Behavioural Disorders
Conditions
Interventions
This study is a three-armed, double-blinded randomized control trial that, to assess the mechanisms of change, compares the efficacy of cognitive control training and bias modification in Major Depres
First et al., 2015), will be used, as well as, the Patient Health Questionnaire-9 (PHQ-9
Kroenke et al., 2001) and the Generalized Anxiety Disorder-7 (GAD-7
Spitzer et al., 2006).
In the baseline assessment, all participants will complete the PHQ-9 (Kroenke et al., 2001), GAD-7 (Spitzer et al., 2006), and the Regulation Emotion System Sur
De France & Hollenstein, 2017). This will be followed, in the same session, by an assessment of attention
Sponsors
Instituto Superior da Maia
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Over 18 years old. 2. Be fluent in Portuguese. 3. Normal or corrected normal vision. 4. Meet the criteria for Major Depressive Disorder or Generalized Anxiety Disorder for inclusion in the clinical groups. In turn, for the inclusion in the Healthy Adults group participants must not have any psychological diagnose.
Exclusion criteria
Exclusion criteria: 1. Meet the criteria for substance abuse, bipolar disorder, and any psychotic disorder or symptoms. 2. Active suicidal ideation or a previous suicide attempt.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Depression symptoms are measured with the Patient Health Questionnaire-9, in all groups and conditions, in the screening, baseline, intervention, and follow-up stages to assess the development of depressive symptoms. 2. Anxiety symptoms is measured using the Generalize Anxiety Disorder-7 in all the sessions and in all groups and conditions. 3. Attentional bias is measured using a Dot-Probe Task in the baseline, intervention, and follow-up stages. 4. Interpretation bias is measured with the Scrambled Sentences Test at baseline, intervention, and follow-up stages. 5. Working memory is measured with the N-back task at baseline, during intervention and follow-up stages. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Emotion regulation strategies are measured with the Regulation Emotion System Survey at baseline, during intervention and follow-up stages. 2. Memory bias is measured with the Self-Referent Encoding Task at baseline, during intervention and follow-up. | — |
Countries
Portugal
Outcome results
None listed