A randomised controlled trial of the use of topical application of tranexamic acid in primary cemented total hip replacement

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN58762744

Enrollment

124

Registered

2006-09-29

Start date

2005-06-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal Diseases: total hip replacement Musculoskeletal Diseases Total hip replacement

Interventions

Randomised controlled trial

Eligibility

Inclusion criteria

Inclusion criteria: Patients having unilateral primary cemented total hip replacement

Exclusion criteria

Exclusion criteria: 1. Allergic to tranexamic acid 2. Pregnancy 3. History of DVT/pulmonary embolus 4. Patients involved in other trials 5. Known bleeding problems 6. Concurrent treatment with warfarin 7. Low dose molecular weight heparin or conventional heparin 8. Paget's disease or revision total hip replacement

Design outcomes

Primary

Measure	Time frame
Reduction in blood loss	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026