Improving physical health and reducing substance use in psychosis

Conditions

Topic: Mental Health Research Network

Fiona Gaughran, Daniel Ståhl, Anita Patel, Khalida Ismail, Shubuladè Smith et al. (18 authors)

Programme Grants for Applied Research2020-01-017 citations

Randomised control trial of the effectiveness of an integrated psychosocial health promotion intervention aimed at improving health and reducing substance use in established psychosis (IMPaCT).

Gaughran F, Stahl D, Ismail K, Greenwood K, Atakan Z, Gardner-Sood P, Stubbs B, Hopkins D, Patel A, Lally J, Lowe P, Arbuthnot M, Orr D, Corlett S, Eberhard J, David AS, Murray R, Smith S, IMPaCT Team.

2017-12-2829 citations

10.1186/s12888-017-1571-0

Randomised controlled trial to improve health and reduce substance use in established psychosis (IMPaCT): cost-effectiveness of integrated psychosocial health promotion

Margaret Heslin, Anita Patel, Daniel Ståhl, Poonam Gardner-Sood, Manyara Mushore et al. (24 authors)

BMC Psychiatry2017-12-0114 citations

10.1186/s12888-017-1570-1

Clinical correlates of vitamin D deficiency in established psychosis.

Lally J, Gardner-Sood P, Firdosi M, Iyegbe C, Stubbs B, Greenwood K, Murray R, Smith S, Howes O, Gaughran F.

2016-03-2239 citations

10.1186/s12888-016-0780-2

Improving physical health and reducing substance use in psychosis--randomised control trial (IMPACT RCT): study protocol for a cluster randomised controlled trial.

Gaughran F, Stahl D, Ismail K, Atakan Z, Lally J, Gardner-Sood P, Patel A, David A, Hopkins D, Harries B, Lowe P, Orr D, Arbuthnot M, Murray RM, Greenwood KE, Smith S.

2013-10-1623 citations

10.1186/1471-244x-13-263

Interventions

Pre-randomisation: Within each of the CMHTs in SLAM, Oxleas and Sussex team leaders who agree to participate in the trial will be asked to present a list of their current care coordinators. These car

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients within consenting CMHTs who meet the following criteria will be recruited to the study: 1. Aged between 18 - 65 years old, either sex 2. Have a diagnosis of psychotic disorder including International Classification of Diseases, version 10 (ICD-10) diagnosis F20-29, F31.2, F32.3, F33.3 but excluding first episode psychotic illness as these patients are participating in another study 3. Are registered on the enhanced level of the Care Approach Programme (CPA)

Exclusion criteria

Exclusion criteria: 1. Patients with primary diagnosis of learning disability 2. Physical health problem that will independently impact on metabolic measures and substance use 3. Pregnancy as a health promotion intervention may interfere with the necessary care 4. Life threatening or terminal medical conditions in which intensive care is already provided

Design outcomes

Secondary

Measure	Time frame
Specific measures related to each module will be carried out at the end of each module, such as: 1. Diabetes module (glycated haemoglobin and fasting glucose) 2. Substance use module (Time Line Follow Back), Nicotine Dependence Questionnaire 3. Exercise (IPAQ) 4. Diet (waist circumference, weight) Measured at baseline, 3 months, 12 months and 24 months.	—

Primary

Measure	Time frame
1. Quality of life (QLS) 2. Metabolic syndrome components: 2.1. Waist circumference 2.2. Resting blood pressure 2.3. Fasting plasma glucose level, HbA1c, HOMA-IR 2.4. Triglyceride levels 2.5. HDL Cholesterol 3. Cost and cost-effectiveness of the HPI 4. Use of substances 5. PANSS score Measured at baseline, 3 months, 12 months and 24 months.	—

Countries

United Kingdom

Outcome results

None listed