A study to identify increased production of aldosterone by the adrenal gland using PET/CT scanning techniques

Image-Derived Enzymatic Adrenal Lateralisation of Primary Aldosteronism

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN58338025

Enrollment

Registered

2022-07-22

Start date

2022-01-04

Completion date

Unknown

Last updated

2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aldosterone producing adenoma Cancer

Interventions

The first four patients enrolled will undergo a 90 minute scan including dynamic injection of 18F-UCB2 in order to identify the optimal imaging time point for scanning. The second four patients will

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with a diagnosis of, and planned surgery for aldosternone producing adnemoma

Exclusion criteria

Exclusion criteria: Inability to understand, or insufficient capacity to give informed consent.

Design outcomes

Primary

Measure	Time frame
Uptake of 18F-UCB2 by the adrenal glands measured using PET/CT scanning techniques following identification, and prior to surgery for adrenalectomy	—

Secondary

Measure	Time frame
Levels of aldosterone synthase identified post operatively in resected adrenals	—

Countries

England, United Kingdom

Contacts

Public ContactRob Shortman

robertshortman@nhs.net-

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Aug 25, 2026