Small for gestational age fetus Pregnancy and Childbirth
Conditions
Interventions
Participants will be recruited directly from the fetal medicine or maternity assessment units at the nominated research sites. All women who meet the eligibility criteria for this study will be invit
Sponsors
University of Liverpool
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Women with a SGA fetus between 32+0 and 37+6 weeks of gestation 2. Singleton pregnancy 3. Age =16 years 4. 32+0 – 37+6 weeks of gestation 5. EFW <10th centile on ultrasound within preceding 72 hours
Exclusion criteria
Exclusion criteria: 1. Unable to give informed consent 2. Known or suspected structural/chromosomal fetal abnormality 3. Absent or reversed EDF in Umbilical Artery on Doppler study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The feasibility of using a maternal biomarker (sFlt-1/PIGF ratio) to refine the care pathway for the management of pregnancies affected by SGA including: 1. Recruitment rate recorded as the number of eligible women who consent to participate in the study during the 12 month recruitment period 2. Attrition rate assessed using the number of women who consent to participate and remain in the study until hospital discharge or their due date, whichever is sooner 3. Acceptability of biomarker led management to women and clinicians assessed by interviews/questionnaires (PLANES Women and Partner Questionnaire) with women and their birth partners following the consent process and clinician focus groups at the end of the 12-month recruitment period | — |
Secondary
| Measure | Time frame |
|---|---|
| There are no secondary outcome measures | — |
Countries
England, United Kingdom
Outcome results
None listed