“Test n Treat”: a feasibility trial of rapid STI testing and treatment

Conditions

Chlamydia trachomatis and Neisseria gonorrhoeae infection Infections and Infestations

Kerry-Barnard S, Huntington S, Fleming C, Reid F, Sadiq ST, Drennan VM, Adams E, Oakeshott P.

2020-04-163 citations

'Test n Treat' (TnT): a cluster randomized feasibility trial of on-site rapid Chlamydia trachomatis tests and treatment in ethnically diverse, sexually active teenagers attending technical colleges.

Oakeshott P, Kerry-Barnard S, Fleming C, Phillips R, Drennan VM, Adams EJ, Majewska W, Harding-Esch EM, Cousins EC, Planche T, Green A, Bartholomew RI, Sadiq ST, Reid F.

2018-11-017 citations

10.1016/j.cmi.2018.10.019

'Test n Treat (TnT)'- Rapid testing and same-day, on-site treatment to reduce rates of chlamydia in sexually active further education college students: study protocol for a cluster randomised feasibility trial.

Kerry-Barnard S, Fleming C, Reid F, Phillips R, Drennan VM, Adams EJ, Majewska W, Balendra A, Harding-Esch E, Cousins E, Tariq Sadiq S, Oakeshott P.

2018-06-052 citations

10.1186/s13063-018-2674-8

Interventions

Participating colleges are randomised to one of two groups using block randomisation to ensure three colleges are allocated to each group. Intervention group: One month after recruitm

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Sexually experienced Further Education College student 2. Aged 16-24

Exclusion criteria

Exclusion criteria: 1. Students who have never had penetrative sexual intercourse 2. Students with severe learning disability

Design outcomes

Primary

Measure	Time frame
1. Recruitment rate is measured as the time taken to recruit 80 participants at each site at recruitment end (1 month) 2. Testing and Treatment uptake rates at three intervention sites are measured by the proportion of the 80 participants at each site who take part in Test and Treat for chlamydia/gonorrhoea at 1 and 3 months after recruitment end 3. Follow up rate is measured at 7 months by: 3.1. Calculating the percentage of participants who provide samples at all sites 3.2. Calculating the percentage who complete the final questionnaires 3.3. Recording the time to treatment for participants who test positive 4. Prevalence of chlamydia/gonorrhoea is measured using PCR of genitourinary samples taken at baseline and 7 months	—

Measure

Time frame

1. Recruitment rate is measured as the time taken to recruit 80 participants at each site at recruitment end (1 month) 2. Testing and Treatment uptake rates at three intervention sites are measured by the proportion of the 80 participants at each site who take part in Test and Treat for chlamydia/gonorrhoea at 1 and 3 months after recruitment end 3. Follow up rate is measured at 7 months by: 3.1. Calculating the percentage of participants who provide samples at all sites 3.2. Calculating the percentage who complete the final questionnaires 3.3. Recording the time to treatment for participants who test positive 4. Prevalence of chlamydia/gonorrhoea is measured using PCR of genitourinary samples taken at baseline and 7 months

—

Secondary

Measure	Time frame
1. Acceptability of TnT in FE colleges is measured through qualitative interviews at 1-9 months after recruitment 2. Cost of implementing TnT in FE colleges compared with usual care (no TnT) is measured by estimating: 2.1. The cost per person screened and treated of implementing TnT in FE colleges compared with usual care (no TnT) 2.2. The incremental cost per chlamydia and gonorrhoea infection averted Costs will be classified as solely research; capital set-up costs; or on-going running costs. Data will be collected in months 1-9, and the analysis conducted in months 10 to 20.	—

Measure

Time frame

1. Acceptability of TnT in FE colleges is measured through qualitative interviews at 1-9 months after recruitment 2. Cost of implementing TnT in FE colleges compared with usual care (no TnT) is measured by estimating: 2.1. The cost per person screened and treated of implementing TnT in FE colleges compared with usual care (no TnT) 2.2. The incremental cost per chlamydia and gonorrhoea infection averted Costs will be classified as solely research; capital set-up costs; or on-going running costs. Data will be collected in months 1-9, and the analysis conducted in months 10 to 20.

—

Countries

United Kingdom

Outcome results

None listed