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Severity of sleep apnoea in chronic obstructive pulmonary disease patients who require non-invasive mechanical ventilation with pressure support guaranteed with average volume

Apnoea-hypopnoea index in COPD exacerbation and AVAPS

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN57632435
Enrollment
30
Registered
2020-01-14
Start date
2013-07-01
Completion date
Unknown
Last updated
2020-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep apnoea, COPD Respiratory Sleep apnoea, COPD

Interventions

Protocol of noninvasive mechanical ventilation for the treatment of acute respiratory failure: When the patient had been diagnosed with ARF in the emergency department, a senior physic
the inspiratory time was 0.8 to 1.2 s. Subsequently, the O2 supplements were added through an O2 adapter close to the mask to keep the SaO2 above 90%. The maximum IPAP, exhaled tidal volume (EVT), Vmi

Sponsors

School of Medicine, Universidad San Francisco de Quito,
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age: 18 and older 2. Admitted to the intensive care unit of Santa Maria Clinic 3. Patients with ventilatory failure secondary to hypercapnia (PaCO2 > 45 mmHg, pH 7.35 or less) 4. Patients with inadequate oxygenation (PaO2 25 breaths per minute) and use of accessory muscles during hospitalization

Exclusion criteria

Exclusion criteria: 1. Hemodynamic instability 2. Noncooperative or agitated 3. Unable to use the interface device 4. Had recent surgery of the upper airway tract 5. Used NIV with a do-not-resuscitate (DNR) order 6. Received some type of sedation during the period of study

Design outcomes

Primary

MeasureTime frame
Severity of sleep apnea measured using the apnoea-hypopnoea index during stay in the emergency department

Secondary

MeasureTime frame
1. Days of hospital stay in the emergency department 2. NIV rates during stay in the emergency department 3. Intubation rates during stay in the emergency department

Countries

Ecuador

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026