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Metabolic and cardiovascular response to common food and drink ingredients

Measuring the acute thermogenic cardiovascular effects of common food and drink ingredients (dietary protein, sugars, methylxanthines & water)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN57611296
Enrollment
150
Registered
2014-10-20
Start date
2013-01-01
Completion date
Unknown
Last updated
2015-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diet-induced thermogenesis Nutritional, Metabolic, Endocrine

Interventions

Interventions 1. Protein: A standardised test meal containing 10 to 40 %kcal protein 2. Sugar: A standardised test drink containing sucrose, glucose, fructose, lactose or galactose dissolved in disti

Sponsors

University of Fribourg (Switzerland)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. 20 ? 40 years old 2. Healthy as determined by medical history 3. Signed consent given

Exclusion criteria

Exclusion criteria: 1. Pregnancy 2. History of eating disorders 3. History of metabolic diseases (e.g. diabetes) 4. History of cardiovascular disease 5. History of neurological or psychiatric disorders 6. History of gastro-intestinal disorders 7. Any other condition that might impair the subject?s ability to participate in the study

Design outcomes

Primary

MeasureTime frame
Energy expenditure will be measured by indirect calorimetry before and after the ingestion of each food/drink ingredient

Secondary

MeasureTime frame
1. Cardiovascular response (heart rate and blood pressure) will be measured by continuous physiological monitoring before, during and after each intervention 2. Body composition will be measured at the start the study 3. Dietary and lifestyle information will be collected by questionnaire 4. Body temperature and habitual physical activity will be measured by wireless physiological monitoring over a period of one week

Countries

Switzerland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026