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Treatment of obesity: effects of micronutrient supplementations and variations of plasma organochlorine concentration on daily energy expenditure and feeding behaviour in obese individuals

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN57519530
Enrollment
80
Registered
2005-09-09
Start date
2001-11-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overweight and obese individuals. Nutritional, Metabolic, Endocrine Obesity

Interventions

Experimental group: Energy restriction of approximately -700 kcal/day during 15 weeks. Daily consumption of a multi-vitamin supplement during 15 weeks. Control group: Energy restriction of approximate

Sponsors

Laval University, Quebec (Canada)
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Body Mass Index (BMI) between 30 kg/m^2 and 40 kg/m^2 2. Aged 23 - 47 years old, non-menopaused women 3. Weight circumference of 90 4. Stable body weight during 6 months prior to study 5. Non-smoking 6. Sedentary (less than 1 hour/week of continuous physical activity)

Exclusion criteria

Exclusion criteria: 1. Abnormal blood pressure values 2. Use of medication that could potentially interfere with the study's objectives 3. Consumption of vitamin and mineral supplements 6 months prior the beginning of the study

Design outcomes

Primary

MeasureTime frame
Accentuated body weight and fat mass loss in multivitamin and mineral supplemented group.

Secondary

MeasureTime frame
1. Attenuation of the reduction in daily and resting energy expenditure following body weight loss in the multi-vitamin supplemented group 2. Attenuation of the decrease in fat oxidation following body weight loss in the multi-vitamin supplemented group 3. Attenuation of the increase in appetite-related variables and energy intake following energy deficit and body weight loss in the multi-vitamin supplemented group 4. Decrease in energy expenditure following body weight loss, which will be accompanied by an increase in organochlorine plasma concentration

Countries

Canada

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026