Manchester vascular access study

Understanding haemodialysis vascular access maturation: a prospective observational study to understand the natural history and biology of AV access maturation and identify risk factors for AVF failure

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN57422410

Enrollment

250

Registered

2014-04-03

Start date

2011-10-20

Completion date

Unknown

Last updated

2020-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: Renal disorders

Interventions

Extra bloods at baseline: Patients will have an extra blood test at this point for haematological/biochemical parameters and DNA/stem cell sampling and analysis. Extra blood tests will be optional and

blood tests will be optional and are not mandatory for study inclusion. US scan - follow-up, Doppler ultrasound scan will be used to assess maturation. It is anticipated that most pat

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. The participant is in need of AV dialysis access for haemodialysis. 2. Participant is available and can return for follow-up visits Target Gender: Male & Female ; Lower Age Limit 18 years

Exclusion criteria

Exclusion criteria: Inability to give consent and comply with the study follow-up schedule

Design outcomes

Primary

Measure	Time frame
Successful (unassisted) maturation defined as either A or B A: Use of the AVF with two needles	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026