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Clinical efficacy of ultra-laser irradiation combined with gabapentin on elderly patients with cervical spondylotic radiculopathy

A randomized controlled trial on the clinical efficacy of ultra-laser irradiation combined with gabapentin in the treatment of elderly patients with cervical spondylotic radiculopathy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN57406480
Enrollment
160
Registered
2025-03-13
Start date
2024-06-18
Completion date
Unknown
Last updated
2026-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical spondylotic radiculopathy Musculoskeletal Diseases

Interventions

Patients are divided into the observation group and control group 1:1 with the help of a random number table. Observation group: Ultra-laser irradiation + gabapentin (oral capsules, starting dose 300

Sponsors

The First People's Hospital of Fuyang District, Hangzhou
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 120 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed with cervical spondylotic radiculopathy according to Rehabilitation Guidelines for Diagnosis and Treatment of Cervical Spondylosis (2010) 2. Aged =60 years 3. No history of peripheral nerve disease 4. No severe systemic diseases (cardiovascular, respiratory, digestive, liver, kidney disorders) 5. No opioid, NSAID, antidepressant, or antiepileptic drug use in the past month 6. Willingness to participate and signed informed consent

Exclusion criteria

Exclusion criteria: 1. Severe osteoporosis or bone tuberculosis 2. Nerve-related disorders not caused by cervical spondylotic radiculopathy (e.g., thoracic outlet syndrome, carpal tunnel syndrome, scapulohumeral periarthritis) 3. Severe cardiovascular, cerebrovascular, hepatic, renal, or hematopoietic diseases 4. Poor treatment adherence or incomplete clinical data 5. Congenital musculoskeletal disorders (e.g., congenital torticollis, congenital myopathy)

Design outcomes

Primary

MeasureTime frame
Pain relief measured by the Numerical Rating Scale (NRS/NPRS) at baseline and after three courses of treatment

Secondary

MeasureTime frame
1. Health-related quality of life improvement assessed by EuroQol-five dimensions (EQ-5D) questionnaire at baseline and after treatment 2. Incidence of adverse reactions (gastrointestinal discomfort, dizziness, lethargy, edema, rash, ataxia, fatigue) recorded throughout the study

Countries

China

Contacts

Public ContactZhou Yu
yuz0531@163.com+86 (0)15825525395

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: May 22, 2026