Towards rational prescribing of antibiotics for acute rhinosinusitis: evaluation of the impact and costs of implementation strategies based on a multidisciplinary evidence-based guideline

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN57375471

Enrollment

540

Registered

2005-07-25

Start date

2004-07-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Implementation of a practice guideline for acute rhinosinusitis in general practice Respiratory Rhinosinusitis

Interventions

Cluster randomised factorial trial with 4 study arms. Interventions: academic detailing visits to individual GPs and/or group sessions of GPs on the key messages of the guideline. Control: no specific

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Local peer review groups of general practitioners in Flanders, Belgium (approximately 10-20 GPs per group) are invited to participate.

Exclusion criteria

Exclusion criteria: Groups that have participated in the field testing of the guideline, groups that have been visited by academic detailers more than once in the past, groups located at >1 hour drive from the study centres.

Design outcomes

Primary

Measure	Time frame
Antibiotic prescription rate, cost-effectiveness.	—

Secondary

Measure	Time frame
Choice of antibiotic, use of personalized non-drug prescriptions, clinical course of rhinosinusitis as reported in patient diaries.	—

Countries

Belgium

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026