Standardized cognitive training for MS patients

Metacognitive and functional Training intervention for patients with MS

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN57222203

Enrollment

285

Registered

2016-05-25

Start date

2016-04-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis (MS) Nervous System Diseases Multiple Sclerosis (MS)

Interventions

Participants are allocated to one of three groups sequentially (no randomisation). Intervention group 1: Participants receive standard care as well as metacognitive training (MaTiMS). The MaTiMS sess

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. MS (McDonald-criteria (RRMS, PPMS, SPMS) 2. Expanded Disability Status Scale Score (EDSS) < 6.5) 3. Perceived neuropsychiatric deficits 4. Interest to participate 5. To be in a rehabilitation centre 6. Aged 18-80 years

Exclusion criteria

Exclusion criteria: 1. Probable MS 2. Neuromyelitis Optica 3.SDMT < -2,5 SD

Design outcomes

Primary

Measure	Time frame
Perceived cognitive deficits measured using the perceived deficit questionnaire (PDQ) at baseline, 3 weeks, 3, 6 and 12 months.	—

Secondary

Measure	Time frame
1. Coping and self-efficacy are measured using the Coping Self Efficacy Scale (CSES) at baseline, 3 weeks, 3, 6 and 12 months 2. Fatigue is measured using the Fatigue Scale for Motor and Cognition (FSMC) at baseline, 3 weeks, 3, 6 and 12 months 3. Working Memory is measured using the Corsi-Block-Test / Digit Span backward (Wechsler Memory Scale revised) at baseline, 3 weeks, 3, 6 and 12 months	—

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026