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Assessing the additional neoplasia yield of EndoRings™ in a colorectal cancer (CRC) screening setting

To assess the additional yield of colorectal neoplasia at colonoscopy with EndoRings™ in a colorectal cancer (CRC) screening setting: a multicentre randomized trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN56854419
Enrollment
900
Registered
2016-07-12
Start date
2016-08-01
Completion date
Unknown
Last updated
2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal adenomas and serrated polyps Cancer

Interventions

The EndoRings is a flexible silicone rubber add-on device designed to be attached to the distal tip of the designated endoscope. The product features a short tube like shape with two flexible circular

Sponsors

ASL RM1
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Subjects positive at immunochemical fecal test at organized screening program in countries where organized programs are running 2. Sporadic screening in those countries where programs are not running

Exclusion criteria

Exclusion criteria: Previous colonoscopy in 5 years

Design outcomes

Primary

MeasureTime frame
Detection rate of (advanced) neoplasia with and without EndoRIng (95% CI)

Secondary

MeasureTime frame
1. Detection rate of adenoma/polyp/flat adenoma/serrated polyps/adenomas, determined though colonoscopy results from each of the study arms 2. Detection rate of neoplasia by colonic site: distal (rectum, sigmoid and descending colon) and proximal (proximal to the descending colon) 3. Time required to reach the cecum, as measured in minutes during the insertion of the scope from the anus to the caecum 4. Withdrawal time, as measured in minutes during the withdrawal of the scope from the caecum to the anus 5. Patient’s experience, as measured with a visual analogue scale rated from 1 to 7

Countries

Italy, Netherlands, Spain

Contacts

Public ContactCesare Hassan
cesareh@hotmail.com+390658446608

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026