Hyperemesis gravidarum / severe nausea and vomiting in pregnancy Pregnancy and Childbirth Hyperemesis gravidarum
Conditions
Interventions
On admission, all women will be offered an anti-emetic injection (cyclizine lactate, 50 mg), and given an advice leaflet detailing helpful measures to reduce symptoms. They will be given a study infor
Sponsors
Newcastle upon Tyne Hospitals NHS Trust (UK)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Any woman attending the maternity assessment unit under 20 weeks gestation suffering from moderate or severe nausea and vomiting
Exclusion criteria
Exclusion criteria: 1. Poor/no English 2. Over 20 weeks gestation 3. Under 16 year old or over 45 years 4. No treatment warranted 5. Women with significant medical conditions, e.g., insulin-dependent diabetes mellitus (IDDM), renal disease, cardiac disease 6. Women not suitable for out-patient management 7. Three admissions or more in the same week
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Whether rapid rehydration administered over six hours in a day care setting, combined with out-patient psychological support reduces in-patient stay and improves women's quality of life. | — |
Secondary
| Measure | Time frame |
|---|---|
| The cost consequences of rapid rehydration on an out-patient basis compared to the current policy of routine admission. | — |
Countries
United Kingdom
Outcome results
None listed