Skip to content

Glucose-insulin-potassium infusion in patients treated with primary percutaneous coronary intervention for acute myocardial infarction

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN56720616
Enrollment
940
Registered
2005-05-20
Start date
1998-04-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ST elevation myocardial infarction (mi) Circulatory System Acute myocardial infarction

Interventions

After admission, patients were randomly assigned to either glucose-insulin-potassium (GIK) infusion or no infusion. In patients randomized to GIK, a continuous infusion of 80 mmol potassium chloride i

Sponsors

Netherlands Heart Foundation (Netherlands)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All consecutive patients with symptoms consistent with acute MI of >30 min duration, presenting within 24 hours after the onset of symptoms and with an ST-segment elevation of more than 1 mm (0.1 mV) in two or more contiguous leads on the electrocardiogram, or new onset left bundle branch block, were evaluated for inclusion in this single-center study. Patients presented at our center and patients referred for treatment of high-risk myocardial infarction (MI) from nine referring hospitals without angioplasty facilities were included.

Exclusion criteria

Exclusion criteria: Patients were excluded when pre-treated with thrombolysis or when an illness associated with a marked restricted life expectancy was present.

Design outcomes

Primary

MeasureTime frame
30-day mortality

Secondary

MeasureTime frame
Recurrent infarction, repeat coronary angioplasty, and the composite incidence of death, recurrent infarction, or repeat coronary angioplasty.

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026