Depressive disorder/ bipolar disorder Mental and Behavioural Disorders Depressive episode
Conditions
Interventions
Ultrabrief bifrontal ECT vs ultrabrief unilateral ECT. Patients were treated twice weekly until remission and had a mean number of treatment sessions of 11.
Ultrabrief pulse ECT = pulse width of 0.3
Sponsors
Catholic University Leuven (Belgium)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 18 years or older 2. Patients with Diagnostic and Statistical Manual of mental disorders fourth edition (DSM-IV)-defined major depressive disorder, either bipolar or unipolar, with or without psychotic symptoms 3. Those who were referred for ECT 4. Those who had a minimum baseline score of 18 on the 17-item Hamilton Rating Scale for Depression (HRSD) 5. Written informed consent
Exclusion criteria
Exclusion criteria: 1. Schizophrenia 2. Neurological illness 3. Cognitive disorder 4. Substance abuse or dependence within the previous year 5. ECT within the past 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The following were performed at baseline and once every week until response/remission, and 1 and 6 weeks after finishing the course, by a blinded rater: 1. Hamilton Depression Rating Scale (HDRS) 2. Beck Depression Inventory (BDI) 3. Clinical Global Impression (CGI) 4. Patient Global Impression (PGI) | — |
Secondary
| Measure | Time frame |
|---|---|
| The following were assessed at baseline and 1 and 6 weeks after finishing the course: 1. Mini Mental State Examination (MMSE) 2. Trail Making Test A&B 3. Continuous Performance Task (CPT) 4. Wisconsin Card Sorting Test (WCST) 5. Rey's Auditory Verbal Learning Test (RAVLT) 6. Letter Number Sequencing (WAIS) 7. Autobiographical Memory Test (AMT) 8. Autobiographical Memory Interview (AMI) 9. Squire Subjective Memory Questionnaire (SSMQ) | — |
Countries
Belgium
Outcome results
None listed