Specialty: Respiratory disorders, Primary sub-specialty: COPD Respiratory COPD
Conditions
Interventions
Patients will be enrolled into one of two cohorts:
1. Stable patients with chronic hypercapnia (raised blood levels of CO2). They will be monitored in the community (community-based c
in-patients will undergo clinical assessment of COPD following admission and before discharge from hospital. All patients will be assessed a further 3 times: during the second and fourth week in the c
Sponsors
Cambridge Respiratory Innovations Ltd
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients of either sex, age 18 years and over, diagnosed with COPD, who have given written, informed consent 2. Patients in the case-managed group will have chronically elevated partial pressure of carbon dioxide (PaCO2) and will be susceptible to frequent exacerbations of COPD 3. Patients in the acute admission group will have been admitted to hospital via the emergency room for treatment of COPDrelated ventilatory failure
Exclusion criteria
Exclusion criteria: 1. Diagnosis of neuromuscular disorders or kyphoscoliosis 2. Patients who, in the opinion of the investigator are unlikely to comply with the requirements of the study, use the device correctly, or keep the diary records
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in exhaled CO2 profiles obtained by the N-Tidal C data-collector capnometer. The reading, which typically takes 60 seconds to collect, will be repeated three times daily, for a period of six weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcome measures | — |
Countries
United Kingdom
Contacts
Public ContactRavi Mahadeva
Outcome results
None listed