Acute myocardial infarction Circulatory System
Conditions
Interventions
The aim of this study is to evaluate the effect of using index microcirculatory resistance (IMR) to guide hospital discharge and its impact on the strength of heart muscle in patients presenting with
Sponsors
Newcastle upon Tyne Hospitals NHS Foundation Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients aged 18-90 years presenting with ST-segment elevation myocardial infarction (STEMI)
Exclusion criteria
Exclusion criteria: 1. Patients in whom safety or clinical concerns preclude participation 2. Pregnant or breastfeeding female 3. Suboptimal angiographic results such as final slow flow or distal embolization 4. Need for in-hospital staged percutaneous coronary intervention (PCI) 5. Cardiogenic shock 6. Pulmonary oedema or severe heart failure requiring diuretics treatment during or immediately after the procedure 7. Contraindication to adenosine 8. Standard contra-indications to MRI such as claustrophobia 9. Known allergy to any other component of xience stent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left ventricle function (strength of heart muscle) measured using cardiac magnetic resonance imaging.at 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Clinical events measured using GP/ hospital records and patient contact at 1 year 2. Clot volume during acute heart attack measured using optical coherence tomography at the time of acute heart attack presentation 3. Health status measured using Seattle questionnaire at 3 months | — |
Countries
England, United Kingdom
Contacts
Public ContactMohammad Alkhalil
Outcome results
None listed