Individuals with high myopia Eye Diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Sphere = -6.00 diopter (cylinder is not included) in both eyes 2. Aged between 7 and 70 years old
Exclusion criteria
Exclusion criteria: 1. Secondary myopia, such as a history of retinopathy of prematurity or neonatal problems, or syndromic myopia with a known genetic disease or connective tissue disorders, such as Stickler or Marfan syndrome 2. History of laser treatment for myopia correction or any intraocular surgery affecting refractive status 3. Have autoimmunity disease such as systemic lupus erythematosus, rheumatoid arthritis; 4. Have severe health problems precluding follow-up such as end-stage heart disease, kidney disease, lung disease, or terminal cancer 5. Have significant ocular media opacity preventing fundus examinations (e.g.dense corneal opacity) 6. Unable to give their own informed consent 7. Plan to move from the area within the next 8 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The long-term development and progression of myopic maculopathy measured using fundus photography and optic neuropathy measured using optical coherence tomography and visual field in highly myopic populations and associated risk factors at baseline and each follow-up visit (2, 4, 6, and 8 years). | — |
Secondary
| Measure | Time frame |
|---|---|
| There are no secondary outcome measures | — |
Countries
China