Communication And Low Mood (CALM) study

Communication and Low Mood: a multicentre randomised controlled trial of behaviour therapy aimed at improving mood in people with aphasia following a stroke

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN56078830

Enrollment

Registered

2010-06-24

Start date

2005-10-21

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: Stroke Research Network, Mental Health Research Network

Interventions

Behaviour therapy: This consists of up to 20 one hour sessions of therapy for up to three months from an assistant psychologist delivered at the patient's place of residence (e.g. at home, in hospital

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Stroke 2. Aphasia 3. Low mood (greater than 6 on Stroke Aphasic Depression Questionnaire Hospital Version [SADQ-H] or greater than 50 on "sad" subscale of Visual Analogue Mood Scales [VAMS]) 4. Aged at learst 18 years old, either sex

Exclusion criteria

Exclusion criteria: 1. Dementia 2. Blind or deaf 3. Received treatment for depression in the five years prior to stroke

Design outcomes

Primary

Measure	Time frame
Stroke Aphasic Depression Questionnaire (SADQ; 21 item hospital version), measured 3 and 6 months after randomisation.	—

Secondary

Measure	Time frame
Measured 3 and 6 months after randomisation: 1. Visual Analogue Mood Scales (VAMS) 'sad' item 2. Visual Analogue Self-Esteem Scale (VASES)	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026