Improving the metabolic competence in oocytes of PCOS patients undergoing IVF treatment. Pregnancy and Childbirth
Conditions
Interventions
Patients providing informed consent are randomized for treatment or no treatment. Randomization is based on a computer-generated randomization list comprising 12 blocks of 4 positions each, total 48 p
Sponsors
Acibadem Healthcare
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. PCOS patients diagnosed using Rotterdam's Criteria 2. Primary infertility for at least 1 year 3. No other condition leading to infertility
Exclusion criteria
Exclusion criteria: Patients who requested two embryos but implanted only one.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical pregnancy, calculated as number of fetuses with heart activity beyond 20 weeks of gestation per transferred embryo | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. FSH consumption during stimulation, calculated as cumulative number if FSH units injected 2. Fertilization rate, calculated as the rate of fertilized oocytes (2 PN) out of the total number of inseminated oocytes 3. Blastocyst rate, calculated as the rate of fertilized oocytes reaching the blastocyst stage at 5-6 days 4. Biochemical pregnancy, calculated as the rate of positive hCG at 7 days post embryo transfer out of the number of patients receiving an embryo transfer | — |
Countries
Turkey
Outcome results
None listed