A study to see whether we can increase the pain-free period in upper limb surgeries with regional anaesthesia block by adding dexmedetomidine to low-dose levobupivacaine

A comparative study of the effect of 0.25% levobupivacaine in ultrasound-guided supraclavicular brachial plexus block

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN55964940

Enrollment

Registered

2021-11-15

Start date

2018-02-20

Completion date

Unknown

Last updated

2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elective upper limb surgery Surgery

Interventions

60 ASA I and II patients aged between 18 to 60 years of either sex undergoing elective upper limb surgery lasting more than 30 minutes were included in the study. They were divided into two groups of

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Undergoing elective upper limb surgery lasting more than 30 minutes 2. Aged 18-60 years 3. American Society of Anesthesiologists Classification (ASA) I and II

Exclusion criteria

Exclusion criteria: 1. Hypertension 2. Uncontrolled diabetes 3. Arrhythmia 4. Renal failure 5. Liver failure 6. Bleeding tendencies 7. Pregnant 8. Neuropathy

Design outcomes

Primary

Measure	Time frame
1. Sensory block assessed by atraumatic pinprick test using a three-point scale at 3, 6, 12, 15, 18, 21, 24, 27, 30 min 2. Motor block assessed using the Modified Bromage three-point scale at 5, 10, 15, 20, 25 and 30 min, and thereafter every 15 min for 2 h and then 30 min until the block effect has resolved 3. Sedation score assessed by the Ramsay sedation scale at 0, 5, 10, 15, 20, 25, 30 min 4. Pain assessed using a visual analogue scale (VAS) 0-10 at 0, 5, 10, 15, 20, 30 min, then hourly for 24 hours	—

Measure

Time frame

1. Sensory block assessed by atraumatic pinprick test using a three-point scale at 3, 6, 12, 15, 18, 21, 24, 27, 30 min 2. Motor block assessed using the Modified Bromage three-point scale at 5, 10, 15, 20, 25 and 30 min, and thereafter every 15 min for 2 h and then 30 min until the block effect has resolved 3. Sedation score assessed by the Ramsay sedation scale at 0, 5, 10, 15, 20, 25, 30 min 4. Pain assessed using a visual analogue scale (VAS) 0-10 at 0, 5, 10, 15, 20, 30 min, then hourly for 24 hours

—

Secondary

Measure	Time frame
1. Duration of analgesia measured using visual analogue scale hourly until the patient complains of pain over 24 h 2. Adverse events measured including hypotension, bradycardia, drop-in saturation, recorded by continuous monitoring for 24 h	—

Countries

India

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026