Adult-type hypolactasia Nutritional, Metabolic, Endocrine Lactose intolerance
Conditions
Interventions
The study sample includes the group of students from Northern State Medical University. All subjects have previously undergone genotyping for detection of lactase persistent/non-persistent genotype. A
Sponsors
Oy Verman Ab (Finland)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Students from medical university with previously confirmed lactase non-persistent genotype (C/C-13910), aged 17 - 26 years, either sex 2. Students are included into study regardless of previous diseases, gastrointestinal symptoms, either connected or not with milk intake 3. All subjects will be fasting overnight before study and will be asked to avoid lactose content products 2 days before the study 4. Subjects will be asked to avoid lactose-containing food during 3 hours after the milk load with lactase enzyme or placebo
Exclusion criteria
Exclusion criteria: 1. Inability or refusal to sign informed consent 2. Students younger or older than age of study group
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Five symptoms connected to lactose intolerance will be estimated by using the scale of severity where 1 is the minimal severity and 10 is maximum. Zero means no symptom. Subjects will fill in the table of severity of symptoms before intervention, 1 hour, 2 hours and 3 hours after the intervention and the rest of day after lunch. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcome measures | — |
Countries
Russian Federation
Outcome results
None listed