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Immune response to the BNT162b2 vaccine against the COVID-19 virus in healthcare workers and immunocompromised patients

Study of immunogenicity and effectiveness of BNT162b2 in healthcare workers and oncological/immunocompromised patients at Istituti Fisioterapici Ospitalieri.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN55371988
Enrollment
2000
Registered
2021-02-24
Start date
2021-01-27
Completion date
Unknown
Last updated
2024-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19 (SARS-CoV-2 infection) in health-care-workers and oncological/immunocompromised patients Infections and Infestations COVID-19 (SARS-CoV-2 infection)

Interventions

Data on the participants’ sociodemographic and health characteristics will be collected using a questionnaire, and participants will be stratified by age, sex, and body mass index (BMI). The mRNA va

Sponsors

Istituti Fisioterapici Ospitalieri
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Provided written informed consent 2. Oncological/immunocompromised patient at the Istituti Fisioterapici Ospitalieri (IFO) or health worker employed at the Istituti Fisioterapici Ospitalieri 3. Vaccinated at the Istituti Fisioterapici Ospitalieri

Exclusion criteria

Exclusion criteria: 1. Evidence of current or previous SARS-CoV-2 infection by either anamnesis, serological or microbiological test through nasopharyngeal swab before enrolment

Design outcomes

Primary

MeasureTime frame
1. Presence of antibodies measured using blood tests analysed by the LIAISON® SARS-CoV-2 S1/S2 IgG, test at baseline, 22 and 28 days, and every 30 days until the end of the study

Secondary

MeasureTime frame
1. SARS-CoV-2 infection measured using a nasopharyngeal swab analysed by SARS-CoV-2 RT-PCR testing at baseline, 22 and 28 days, and every 30 days until the end of the study

Countries

Italy

Contacts

Public ContactRaul Pellini
raul.pellini@ifo.gov.it+39(0)652666765

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026