Urological surgery procedures Surgery
Conditions
Interventions
According to EAU guidelines and pre-hospitalization protocols, all eligible patients will undergo the following clinical/instrumental assessments:
• Historical and physical examination
Sponsors
European Urological Center C.Ur.E SRL/STP
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients older than 18 undergoing the following urological surgery procedures: 1. Radical caste Tommy 2. Surgery for benign prostatic obstruction 3. Radical and partial nephrectomy 4. Radical nephroureterectomy 5. Radical prostatectomy 6. Ureterolithotripsy 7. Orchifunicolectomy
Exclusion criteria
Exclusion criteria: Patients who, due to age or clinical condition, are unable to receive the information and to sign the informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inflammation indexes will be calculated by the neutrophils/lymphocytes, neutrophils/monocytes, lymphocytes/platelets, CPR, PCT, Albumin, fibrinogen, modified Glasgow prognostic score (mGPS) measured at the time of surgery and at post-operative evaluations using blood and urine samples | — |
Secondary
| Measure | Time frame |
|---|---|
| Obtained by review of medical records at baseline and at follow up appointments: 1. Lifestyles, physical activity and metabolic syndrome measured using: smoker status, BMI, hypertension, diabetes, dyslipdemia, COPD, ECOG, NYHA. 2. Frailty index measured using; questionnaire G8; sFI calculated including the precence of diabetes, functional status of patient before surgery, COPD, heart failure, hypertension; Charlson Comorbidity index. 3. Disease progression, disease-free survival, in patients with cancer of the urogenital system 4. measured using: overall survival (months) and recurrence free survival (months) 5. Histological characteristics of urogenital cancers measured using histopathological reports. 6. Histological inflammation measured using histopathological reports. 7. Main urodynamic parameters in patients undergoing benign prostatic obstruction surgery 8. measured using Uroflowmetry maximum urinary flow (Qmax), voided volume and post void residual 9. Functional recovery after urological surgery (assessed as sexual activity, ejaculation disorders, infertility and urinary incontinence) measured using IPSS, PUF, NIH-CPSI, IIEF questionnaires. | — |
Countries
Italy
Outcome results
None listed