Benefits of tai chi training vs strength training combined with the mental stimulation of an ICOPE program on physical and mental functional capacity in older adults

Effect of tai chi training vs strength training combines with mental stimulation on physical and cognitive functional capacity in older adults within the framework of ICOPE

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN55261971

Enrollment

120

Registered

2025-06-03

Start date

2024-06-06

Completion date

Unknown

Last updated

2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Physical and mental functional capacity in older adults Other

Interventions

All participants provide written informed consent before being included in the study. Groups will be randomly assigned using the Oxford Minimization and Randomization (OxMaR) software. Group 1: Tai

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Adults aged 60 to 74 years. 2. No uncontrolled chronic non-communicable diseases. 3. No severe cognitive problems assessed with the Montreal Cognitive Assessment (MoCa) scale. 4. No terminal illnesses. 5. Sedentary in the past 6 months (less than 60 minutes of moderate-intensity aerobic activity per week and no regular resistance training).

Exclusion criteria

Exclusion criteria: 1. Older adults who do not wish to participate in the study. 2. Who do not have signed informed consent. 3. With uncontrolled chronic non-communicable diseases. 4. With limitations in physical or cognitive functional capacity.

Design outcomes

Primary

Measure	Time frame
1. Cognitive functions measured using the Neuropsychological Assessment Battery: (i) Verbal fluency by category (animals); (ii) Memory using a 10-word list; (iii) Praxias; (iv) Trail Making tests A and B; (v) Montreal Cognitive Assessment (MoCA). 2. Physical performance assessed using the Short Physical Performance Battery (SPPB). 3. Body composition assessed using single-frequency bioelectrical impedance (BIA) using RJL equipment. 4. Muscle strength assessed using a Jamar handheld hydraulic dynamometer with a measurement range of 0 to 100 kg. 5. Biochemical markers of oxidative stress and inflammation: total pro-oxidant capacity, total antioxidant capacity, and markers of chronic inflammation (IL-1, IL-6, IL-8, IL-10, TNF-a). All measured at 12 months	—

Measure

Time frame

1. Cognitive functions measured using the Neuropsychological Assessment Battery: (i) Verbal fluency by category (animals); (ii) Memory using a 10-word list; (iii) Praxias; (iv) Trail Making tests A and B; (v) Montreal Cognitive Assessment (MoCA). 2. Physical performance assessed using the Short Physical Performance Battery (SPPB). 3. Body composition assessed using single-frequency bioelectrical impedance (BIA) using RJL equipment. 4. Muscle strength assessed using a Jamar handheld hydraulic dynamometer with a measurement range of 0 to 100 kg. 5. Biochemical markers of oxidative stress and inflammation: total pro-oxidant capacity, total antioxidant capacity, and markers of chronic inflammation (IL-1, IL-6, IL-8, IL-10, TNF-a). All measured at 12 months

—

Secondary

Measure	Time frame
1. Psychological variables and sleep: depressive symptoms, sleep, well-being, and quality of life will be assessed according to standardized protocols at the Gerontology Research Unit. 2. Advanced activities of daily living: The questionnaire to assess advanced activities of daily living developed by Dias et al. (2019) will be administered. All measured at 12 months	—

Countries

Mexico

Contacts

Public ContactVíctor Manuel Mendoza-Núñez

mendovic@unam.mx+52 55 5623-0721

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026