Enamel erosion Oral Health
Conditions
Interventions
Participants will wear a palatal appliance that is positioned in the roof of their mouth and contains 2 enamel samples. Participants are asked to rinse one of the study toothpastes (a slurry of 3g too
Sponsors
The Procter and Gamble Company
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Provide written informed consent to participate in the study, and receive a copy of the signed consent form 2. Agree not to participate in any other oral/dental product studies during the course of the study 3. Agree to delay any elective dentistry (including dental prophylaxis) until the study has been completed 4. Agree to refrain from the use of any non-study dentifrice or other oral hygiene products for the duration of the study 5. Agree to return for all scheduled visits and follow study procedures 6. 18 years and older 7. Agree to refrain from taking an acidic medication (pH <5.3) during the course of the study 8. Be in good general health, as determined by the Investigator/designee based on a review of the health history/update for participation in the study
Exclusion criteria
Exclusion criteria: 1. Susceptibility to acid regurgitation 2. Recurrent or regular aphthous ulcers 3. Dental erosion or a previous history of being susceptible to high dental erosion after drinking sports drinks or juices 4. Excessive gingival inflammation 5. Severe periodontal disease, as characterized by purulent exudate, generalized mobility, and/or severe recession 6. Any pre-existing oral or medical condition that the examiner determines may place the subject at increased health risk from study participation 7. Non-removable mouth or tongue jewellery 8. Any subject who in the opinion of the investigator (or medically qualified designee) should not participate in the study 9. Personnel, i.e. an employee of the Sponsor, member of the Clinical Trials Unit at the Bristol Dental School and Hospital or family relative. Employees of the Bristol Dental School and Hospital or Bristol University not associated with the Clinical Trials Unit are eligible to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dental erosion measured by profilometry at baseline and Day 10 | — |
Secondary
| Measure | Time frame |
|---|---|
| There are no secondary outcome measures | — |
Countries
England, United Kingdom
Outcome results
None listed