Asthma Respiratory
Conditions
Interventions
Participants will complete some baseline measures of lung function and psychological measures. They will then complete the key outcome measures (computer tasks, and anxiety-related questionnaires) DUR
Sponsors
University of Southampton
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adult (over 18 years) 2. Confirmed diagnosis of asthma. Asthma severity will be clinically diagnosed according to BTS guidelines from Step 1 [mild intermittent asthma] to Step 4 [persistent poor control], have an FEV1 of 60% or more in order to undergo methacholine challenge
Exclusion criteria
Exclusion criteria: 1. Patients under 18 years of age 2. Comorbid psychological disorders other than anxiety/depression (measured using the MINI 3. neuropsychiatric interview questionnaire) 4. Currently participating in an active asthma intervention study 5. Have had acute exacerbation of asthma (needing a course of oral steroid of increased dose of maintenance steroid) with 28 days of the first intervention study Asthma severity is characterised according to BTS guidelines as Step 5 (continuous or frequent use of oral steroids)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Attentional functioning, measured using the computerized Attention network test 2. Attention biases towards threatening stimuli, measured using a dot-probe task 3. Severity of anxiety, measured using the spielberger state-trait anxiety inventory Measured during vs. after methacholine challenge | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Mindfulness and attention questionnaires, measured using the MAAS and ACS 2. Asthma control/quality of life, measured using the ACQ and AQLQ Measured at baseline | — |
Countries
United Kingdom
Contacts
Public ContactMegan Liddiard
Outcome results
None listed