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Efficacy of Anterior Middle Superior Alveolar nerve block (AMSA) versus Infra Orbital Nerve Block (IONB) for dental pulp and soft tissue anaesthesia in the anterior maxilla

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN55062915
Enrollment
28
Registered
2008-02-22
Start date
2008-01-07
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Local anaesthetic techniques in anterior maxilla Oral Health Local anaesthetic techniques in anterior maxilla

Interventions

Each participant receives 3 different local anaesthetic injections in the mouth in random order (1 injection per visit, 3 visits in total). Methods of local anaesthetic injections: 1. AMSA: 1 mL of

Sponsors

Newcastle Upon Tyne Hospitals NHS Foundation Trust (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Healthy adult volunteers 2. Staff or students at Newcastle University

Exclusion criteria

Exclusion criteria: The volunteer: 1. Individuals under 18 years old 2. Systemic disorders which may place volunteers at risk from local anaesthetic injection for example bleeding disorders, history of infective endocarditis, pregnant women 3. Allergies to local anaesthetic drugs 4. Facial anaesthesia or paraesthesia 5. In dental pain at the time of the trial 6. Individuals unable to give informed consent The teeth to be included: 1. Teeth which respond negatively to baseline pulp testing 2. Key test teeth missing

Design outcomes

Primary

MeasureTime frame
Numbness of upper front teeth following local anaesthetic injection, assessed by electric pulp testing at each visit (Average duration of procedure: 1 hour)

Secondary

MeasureTime frame
1. Injection discomfort, assessed by visual analogue scales after each visit 2. Duration of numbness after local anaesthetic injection, assessed by a questionnaire to record the duration of lip numbness after each visit/injection

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026