Magnetic resonance imaging (MRI) fluoroscopy for imaging childhood gastrointestinal malrotation

Magnetic resonance imaging (MRI) replacement of x-ray fluoroscopy in paediatric imaging: an investigation of gastrointestinal malrotation

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN55042368

Enrollment

Registered

2010-07-07

Start date

2008-11-01

Completion date

Unknown

Last updated

2017-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: Oral and Gastrointestinal, Generic Health Relevance and Cross Cutting Themes

Interventions

All patients volunteering for this study will undergo the conventional XR fluoroscopy examination as per standard practice, followed by an additional MRI examination. The diagnosis of the XR test wil

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. All children between the ages of 0 and 6 years referred for an upper gut XRF contrast study for suspected upper intestinal obstruction, i.e., malrotation 2. Age range: 1 day to 6 years, male and female

Exclusion criteria

Exclusion criteria: 1. Usual MR exclusion criteria will apply, but are highly unlikely in this young age group. They include pregnancy, claustrophobia, cardiac pacemakers, metallic implants, cardiac defibrillator implants, aneurysm clips or metallic heart valves, and cochlear or inner ear implants. These exclusion criteria would apply to all people within the vicinity of the MRI scanner, e.g., the parents/guardians in this study. 2. Previous reaction to the relevant X-ray or MRI contrast media (including gadolinium) 3. Congenital abnormalities that make X-ray fluoroscopy or MR fluoroscopy impractical

Design outcomes

Primary

Measure	Time frame
Can a technique using magnetic resonance MR fluoroscopy be developed to replace the conventional X-ray fluoroscopy methodology? All outcomes will be assessed at the time of the intervention.	—

Secondary

Measure	Time frame
To demonstrate the feasibility of magnetic resonance imaging for this type of paediatric imaging, including an assessment of its technical and diagnostic performance, by direct comparison with the established X-ray fluoroscopy based techniques. After each participant has their MRI scan, the results will be compared with those obtained with the standard X-ray fluoroscopy technique, and scored for sensitivity and accuracy in diagnosing gut malrotation. All outcomes will be assessed at the time of the intervention.	—

Measure

Time frame

To demonstrate the feasibility of magnetic resonance imaging for this type of paediatric imaging, including an assessment of its technical and diagnostic performance, by direct comparison with the established X-ray fluoroscopy based techniques. After each participant has their MRI scan, the results will be compared with those obtained with the standard X-ray fluoroscopy technique, and scored for sensitivity and accuracy in diagnosing gut malrotation. All outcomes will be assessed at the time of the intervention.

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Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026