Backflow hepatic arterial flush of liver graft by hepatic vein occlusion in living donor liver tranplantation

Retrograde arterial flush of the liver graft in living donor liver transplantation: a prospective randomised study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN55021745

Enrollment

Registered

2010-10-19

Start date

2006-06-20

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver transplantation Surgery Transplantation

Interventions

After complete parenchymal dissection of the donor liver and cutting the bile duct, intravenous heparin (2000 U) was given to the donor. Two minutes after heparin injection, the graft was quickly remo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Donors' ages range from 18 to 65 years 2. Recipients' aged under 70 years according to the law in Taiwan

Exclusion criteria

Exclusion criteria: 1. Retransplantation 2. Small- or large-sized grafts (graft-versus-recipient weight ratio, GRWR less than 0.8%, or greater than 5%) 3. Recipients with complete portal vein thrombosis 4. Recipients needing renal replacement therapy before LDT

Design outcomes

Primary

Measure	Time frame
1. Intra-operative haemodynamic changes 2. One-month post-transplantational liver function tests 3. Occurrence rates of acute cellular rejection within first month after transplantation 4. Immediate preservation injuries of the graft livers by retrograde arterial perfusion	—

Secondary

Measure	Time frame
1. Rates of vascular and biliary complications 2. Length of post-operative hospital stay 3. Graft and patient survival rates	—

Countries

Taiwan

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026