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A scaled up structural intervention program versus current national HIV prevention program

Inter-ministerial National Structural Intervention Trial: a stepped wedge trial of HIV prevention in Botswana

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN54878784
Enrollment
300000
Registered
2013-06-11
Start date
2013-08-01
Completion date
Unknown
Last updated
2023-01-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV prevention Infections and Infestations Unspecified human immunodeficiency virus [HIV] disease

Interventions

30 districts randomly assigned to intervention groups, stratified by development status and HIV prevalence. The structural intervention: Activities focus on empowerment of women aged

Sponsors

The Autonomous University of Guerrero (Universidad Autónoma de Guerrero) (Mexico)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: For intervention: All districts will be eligible for randomization to receive the intervention. In each intervention district, all residents aged 15 and above will be eligible. Different intervention activities will address different groups of the population, who will be free to decide whether to take up the offer: 1. Economic empowerment including skills workshop and government structural support offered to women aged 18-24, especially those not in school or employment. 2. Audio-drama discussion groups will be offered to all ages and both sexes 3. Concerting of service provision will include discussions with all local service-providers (all eligible) For impact surveys: Young women and young men aged 15-29 years in 10 clusters (random selection of enumeration areas from the recent census) in each of five intervention and five non-intervention districts.

Exclusion criteria

Exclusion criteria: For intervention: No district will be excluded. Within each intervention district, people not resident in the district will be excluded to minimize contamination (by people in other districts hearing of the interventions and wishing to take advantage of them, thus diluting the measured impact). For impact surveys: Field workers will not interview or take blood samples from anyone they judge to be unable to give informed consent or to understand the survey questions.

Design outcomes

Primary

MeasureTime frame
HIV sero-prevalence among women aged 15-29 years. Outcome measured on completion of the intervention in year 4 and compared with the baseline of the second group of communities

Secondary

MeasureTime frame
Protective knowledge, attitudes, subjective norms, intention to change, agency, discussion of prevention, behaviours related to gender violence and HIV risk and prevention

Countries

Botswana, Mexico

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 10, 2026