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Evaluation of laboratory methods for measuring the composition of breastmilk

The NECTAR study: Evaluation of laboratory methods for measuring the composition of breastmilk

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN54811001
Enrollment
90
Registered
2020-02-18
Start date
2021-03-01
Completion date
Unknown
Last updated
2023-03-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Composition of breast milk Nutritional, Metabolic, Endocrine

Interventions

Study procedures: 1. Lactating mother to express 5-10 ml of breast milk into a sterile container 2. Milk sample transported to NDWRH laboratory for processing e.g. cent

Sponsors

University of Oxford
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Female aged 18 to 45 years in established lactation and >1 week post-partum 2. Able to express breast milk by hand or using a pump device 3. Willing and able to give informed consent for this study 4. Able to understand and speak English

Exclusion criteria

Exclusion criteria: Limited milk supply or not lactating for any reason

Design outcomes

Primary

MeasureTime frame
1. Ability to detect presence of hormones (e.g. insulin, leptin and parathyroid hormone related peptide), with samples analysed within 3 months of collection 2. Ability to detect presence of cells (e.g. mammary epithelial cells and immune cells), with samples analysed within 3 months of collection 3. Ability to detect presence of antibodies (e.g. immunoglobulin A), with samples analysed within 3 months of collection 4. Ability to detect presence of metabolites (e.g. breakdown products of bioactive substances such as serotonin), with samples analysed within 3 months of collection

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026