Ischemic heart disease Circulatory System
Conditions
Interventions
There are two groups, both groups underwent coronary angiography, first group received additional cell therapy, second group serve as control group received only coronary angiography without cell ther
Sponsors
University Hospital of Rostock (Universitätsklinikum Rostock) (Germany)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients between 18-80 years of age 2. Had a documented myocardial infarction (MI) at least 3 months 3. Had a clear-cut demarcated region of the left ventricular dysfunction with and open infarct related coronary artery
Exclusion criteria
Exclusion criteria: 1. Presence of acutely decompensated heart failure with NYHA class of IV 2. Infectious or inflammatory disease 3. Active bleeding 4. Surgery or trauma within 2 months 5. Renal or liver dysfunction 6. Tthrombocytopenia or anemia 7. Alcohol or drug dependency 8. A history of other severe chronic diseases or cancer 9. Unwillingness to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change in global ejection fraction (EF) as well as the size of infarcted area measured baseline and 6 months after coronary angiography in both groups. | — |
Secondary
| Measure | Time frame |
|---|---|
| The functional status by New York Heart Association (NYHA) classification and Brain natriuretic peptide (BNP) level in peripheral blood measured baseline and 6 months after coronary angiography in both groups. | — |
Countries
Germany
Outcome results
None listed