Foetal macrosomia Pregnancy and Childbirth Disorders related to long gestation and high birth weight
Conditions
Interventions
Methods:
Women choosing to enter the study will give written informed consent. Data will be collected on those women approached for study participation and who declined to ensure those
Methods:
Women choosing to enter the study will give written informed consent. Data will be collected on those women approached for study participation and who declined to ensure those participating
Sponsors
Health Research Board (HRB) (Ireland)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Secundigravid women of reproductive age (greater than 18 years and less than 45 years) whose first baby was macrosomic (birth weight greater than 4000 g) will be recruited at first booking visit from the antenatal clinic at the National Maternity Hospital
Exclusion criteria
Exclusion criteria: 1. Diabetes 2. Other medical disorders [3. Weight greater than 120 kg - removed 01/09/2009] 4. Poor previous pregnancy outcome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean birth weight centiles and ponderal indices in each group, measured at 14 weeks, 28 weeks, 34 weeks, at birth and 3 months post-partum | — |
Secondary
| Measure | Time frame |
|---|---|
| Current information as of 01/09/2009: Differences between the two groups in maternal weight gain in pregnancy, measured at 14 weeks, 28 weeks, 34 weeks, at birth and 3 months post-partum Initial information at time of registration: Differences between the two groups: 1. Maternal weight gain in pregnancy 2. Urinary metabolomics 3. Cord insulin, leptin and IGF-1 4. Placental weight, villous and vascular development Outcomes will be measured at 14 weeks, 28 weeks, 34 weeks, at birth and 3 months post-partum | — |
| Current information as of 01/09/2009: Differences between the two groups in maternal weight gain in pregnancy, measured at 14 weeks, 28 weeks, 34 weeks, at birth and 3 months post-partum Initial information at time of registration: Differences between the two groups: 1. Maternal weight gain in pregnancy 2. Urinary metabolomics 3. Cord insulin, leptin and IGF-1 4. Placental weight, villous and vascular development Outcomes will be measured at 14 weeks, 28 weeks, 34 weeks, at birth and 3 months post-partum | — |
Countries
Ireland
Outcome results
None listed