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Construction and validation of axillary lymph node metastasis prediction model for breast cancer

Construction and application of three-dimensional visualization diagnosis method for axillary lymph nodes of breast cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN54288903
Enrollment
1000
Registered
2024-02-27
Start date
2023-03-29
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prediction of axillary lymph node metastasis in breast cancer patients Cancer

Interventions

Researchers will retrospectively collect data from invasive breast cancer patients who had completed lung-enhanced CT and axillary lymph node surgery. The researchers will construct a 3D axillary lymp

Sponsors

Hunan Provincial Science and Technology Department
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Underwent BC surgery at our hospital with postoperative pathology confirming invasive BC 2. Underwent axillary lymph node dissection (ALND) at our hospital 3. Completed a high-resolution, thin-section enhanced CT scan of the lung in our radiology department within one month before surgery 4. Had complete clinicopathological data

Exclusion criteria

Exclusion criteria: 1. Had bilateral primary or metastatic bc 2. Received neoadjuvant therapy (nat) before surgery 3. Had incomplete or poor-quality CT scans, flat scans only, or scans conducted externally 4. Had distant metastatic lesions or concurrent other malignancies

Design outcomes

Primary

MeasureTime frame
Predicting correct classification rate, sensitivity and specificity after axillary surgery measured using 3D visualization techniques to construct predictive models at one time point

Secondary

MeasureTime frame
Predicting misclassification rate, false-positive rate and false-negative rate after axillary surgery measured using 3D visualization techniques to construct predictive models at one time point

Countries

China

Contacts

Public ContactWenjun Yi
yiwenjun@csu.edu.cn+8618608403318

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026