A study testing whether collagen powder helps improve skin

A double-blind, placebo-controlled clinical study to assess the skin benefits of a collagen powder supplement

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN54143120

Enrollment

Registered

2025-09-01

Start date

2022-05-19

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Assess the effect on facial skin appearance of the collagen powder supplement when consumed daily for 8 weeks by women with mild to moderate periocular fine lines and wrinkles, and fine lines, wrinkles, sagging, and lack of radiance on the global face. Skin and Connective Tissue Diseases

Interventions

The research team and study participants were blinded to the treatment assignment and were not made aware of receiving the placebo or the active product. Before the start of the study, SGS Stephens ge

skin smoothn

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Women

Exclusion criteria

Exclusion criteria: Women with limited fine lines and facial wrinkles

Design outcomes

Primary

Measure	Time frame
The following primary outcome measures were assessed at clinical evaluations conducted at visit 1 (baseline), visit 2 (week 4), and visit 3 (week 8): 1. Clinical Grading of Efficacy Parameters: Each subject was clinically graded for fine lines and wrinkles on the periocular area and global face; skin smoothness (visual) on the cheeks; and firmness (sagging) (visual), radiance, and overall appearance of skin condition (healthy) on the global face. 2. Skin elasticity/resilience was measured using triplicate pinch recoil measurements performed on the left crow’s feet area	—

Measure

Time frame

The following primary outcome measures were assessed at clinical evaluations conducted at visit 1 (baseline), visit 2 (week 4), and visit 3 (week 8): 1. Clinical Grading of Efficacy Parameters: Each subject was clinically graded for fine lines and wrinkles on the periocular area and global face; skin smoothness (visual) on the cheeks; and firmness (sagging) (visual), radiance, and overall appearance of skin condition (healthy) on the global face. 2. Skin elasticity/resilience was measured using triplicate pinch recoil measurements performed on the left crow’s feet area

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Secondary

Measure	Time frame
The following secondary outcome measures were assessed at clinical evaluations conducted at visit 1 (baseline), visit 2 (week 4), and visit 3 (week 8), unless stated: 1. Mean skin roughness was measured using the following digital images after study completion: 1.1. Full-face digital images captured using SGS Stephens, Inc. portrait photo station with a Canon Mark II 7D SLR camera and a Canon EF-S 60mm f/2.8 macro lens under visible lighting mode 1.2. Cheek images captured using Antera 3D® imaging system 2. Viscoelastic properties of adjacent skin sites on each subject’s right under-eye orbital bone the skin were measured using a Cutometer MPA 580 3. Skin improvements and product perception were measured using a Sponsor-provided self-assessment questionnaire at week 8	—

Measure

Time frame

The following secondary outcome measures were assessed at clinical evaluations conducted at visit 1 (baseline), visit 2 (week 4), and visit 3 (week 8), unless stated: 1. Mean skin roughness was measured using the following digital images after study completion: 1.1. Full-face digital images captured using SGS Stephens, Inc. portrait photo station with a Canon Mark II 7D SLR camera and a Canon EF-S 60mm f/2.8 macro lens under visible lighting mode 1.2. Cheek images captured using Antera 3D® imaging system 2. Viscoelastic properties of adjacent skin sites on each subject’s right under-eye orbital bone the skin were measured using a Cutometer MPA 580 3. Skin improvements and product perception were measured using a Sponsor-provided self-assessment questionnaire at week 8

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Countries

United States of America

Contacts

Public ContactHeather Hausenblas

hhausenblas@wellnessdiscoverylabs.com+1 9048919746

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026