Hypothyroidism Nutritional, Metabolic, Endocrine Hypothyroidism, unspecified
Conditions
Interventions
In a randomized prospective design, hypothyroid patients taking levothyroxine are randomized to take levothyroxine at one of the following three times during Ramadan: (group 1) at dusk 30 minutes befo
Sponsors
Cleveland Clinic Abu Dhabi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age 18 years or older 2. Hypothyroidism treated with levothyroxine for over 6 months 3. Planning to fast during the month of Ramadan 3. Ability to provide informed consent
Exclusion criteria
Exclusion criteria: 1. Age less than 18 years 2. Inability to provide an informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thyroid function tests (plasma TSH and free-T4) measured on the Roche e601 immunoassay analyzer using the electrochemiluminescence immunoassay (ECLIA) sandwich principle for TSH and the ECLIA competition principle for free-T4, within 3 months before Ramadan and repeated within 6 weeks post-Ramadan | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The impact of age and gender on the primary outcome measure, change in thyroid function tests (see above) from pre-to post-Ramadan 2. Patient compliance and satisfaction with the assigned randomized treatment assessed with a telephone call to each patient at the end of the study | — |
Countries
United Arab Emirates
Contacts
Public ContactSamer El-Kaissi
Outcome results
None listed