In vivo near-infrared fluorescence imaging of aqueous humor outflow structures

In vivo near-infrared fluorescence imaging of aqueous humor outflow structures: a prospective, open, observational single center pilot study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN54005880

Enrollment

Registered

2016-02-12

Start date

2015-05-30

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary open angle glaucoma (POAG) Eye Diseases Primary open-angle glaucoma

Interventions

A solution composed of indocyanine green (ICG) and viscoelastic was injected into the Schlemm's canal using the microcatheter during surgery. Visualization of the tracer was accomplished using the mic

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult patients affected by POAG undergoing canaloplasty

Exclusion criteria

Exclusion criteria: 1. Narrow or closed iridocorneal angle 2. Evidence of any secondary glaucoma 3. Pigmentary dispersion 4. Pseudoexfoliation 5. History of trauma 6. History of uveitis 7. Any type of corneal disease or preceding refractive surgery

Design outcomes

Primary

Measure	Time frame
In vivo visualization of the outflow pathway, using the OPMI PENTERO 900 microscope, measured during surgery	—

Secondary

Measure	Time frame
Assessment of the working and non working portions of the conventional outflow pathway on the basis of the visualization of the portion filled, measured during surgery	—

Countries

Italy

Contacts

Public ContactCiro Costagliola

ciro.costagliola@unimol.it+39 (0)874 4041

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 2, 2026