5000-centistoke silicone oil is a better choice of intraocular tamponade in complicated vitreoretinal cases

Analysis of the rate of emulsification in intraocular silicone oil tamponade of differing viscosity

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN53986599

Enrollment

300

Registered

2017-09-30

Start date

2014-09-01

Completion date

Unknown

Last updated

2017-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitreoretinal cases that were considered to have a high risk of redetachment Eye Diseases Vitreoretinal cases that were considered to have a high risk of redetachment

Interventions

Patients who underwent pars plana vitrectomy and SO tamponade due to complicated vitreoretinal disease are included in the study. All procedures are performed by a single surgeon, using similar surgic

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. The patients who underwent pars plana vitrectomy and SO tamponade due to complicated vitreoretinal diseases 2. Older than 18

Exclusion criteria

Exclusion criteria: Cannot follow up.

Design outcomes

Primary

Measure	Time frame
The rate of silicone oil emusification is measured using the slit lamp to observe the sign of silicone oil emulsification at 1 month, 3 months, 6 months and 12 months.	—

Secondary

Measure	Time frame
1. Retinal redetachment, is defined either as a complete retinal redetachment or if there was a progressive local retinal detachment that could not be confined by laser treatment at any time during the follow-up 2. Cataract progression is determined by one doctor if considered to be visually significant at 12 months 3. Corneal abnormalities measured using slitlamp as a bullous- or band-shaped keratopathy, epithelial- or stromal edema or localized opacities at 6 months and 12 months 4. Raised intraocular pressure (IOP) is measured using non-contact tonometer by IOP of more than 25 mmHg or more than 20 mmHg with antiglaucoma medication at any time during the follow-up 5. Hypotony is measured using non-contact tonometer as IOP of less than 5 mmHg at any time during the follow-up	—

Measure

Time frame

1. Retinal redetachment, is defined either as a complete retinal redetachment or if there was a progressive local retinal detachment that could not be confined by laser treatment at any time during the follow-up 2. Cataract progression is determined by one doctor if considered to be visually significant at 12 months 3. Corneal abnormalities measured using slitlamp as a bullous- or band-shaped keratopathy, epithelial- or stromal edema or localized opacities at 6 months and 12 months 4. Raised intraocular pressure (IOP) is measured using non-contact tonometer by IOP of more than 25 mmHg or more than 20 mmHg with antiglaucoma medication at any time during the follow-up 5. Hypotony is measured using non-contact tonometer as IOP of less than 5 mmHg at any time during the follow-up

—

Countries

China

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026