The evaluation and treatment of cognitive symptoms in patients with multiple sclerosis (MS)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN53885363

Enrollment

Registered

2003-09-12

Start date

2000-11-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple sclerosis (MS) Nervous System Diseases Multiple sclerosis

Interventions

Randomised placebo controlled, single dose, crossover trial with MRI and behavioural endpoints.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 12 Healthy people. 24 Patients.

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
1. Behavioural data during performance of the functional imaging task and in the formal cognitive assessment 2. Absolute measures of signal intensity change in regions of interest in the functional scan 3. Lesion load on T1 and T2 weighted MRI scans 4. The percentage of the white matter in the patient that has T1 values greater than normal	—

Secondary

Measure	Time frame
1. Behavioural effect on other tasks within the neuropsychological battery 2. Possible side effects	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026