Analgesia following total knee replacements Surgery Analgesia
Conditions
Interventions
Spinal Anaesthesia: A fine needle in the lower back. We will give 3 ml of 0.5% heavy Bupivacaine in one group and the same volume in the second group but combined with morphine 7 micrograms/Kg, maximu
Sponsors
Gwent Healthcare NHS Trust (UK)
Eligibility
Inclusion criteria
Inclusion criteria: 1. Primary elective total knee replacement 2. Fit patients of American Society of Anesthesiologists (ASA) classification one to three
Exclusion criteria
Exclusion criteria: 1. Patients who refuse consent 2. Revision surgery 3. Had adverse reaction or a contraindication to the administration of morphine, local anaesthetics, non-steroidal anti-inflammatory drugs, paracetamol, tramadol, centrineuraxial block and peripheral nerve blocks 4. Patient with history of chronic pain other than at the site of joint replacement 5. Used regular strong opioids 6. Renal impairment 7. Liver impairment 8. ASA physical status greater than three
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of pain relief on movement of knee joint. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome measures include: 1. The number of patients requiring rescue analgesia 2. Time for the first dose of Tramadol 3. The incidence of the adverse effects of Morphine and Visual Analogue Scale (VAS) for patient satisfaction at 48 hours | — |
Countries
United Kingdom
Outcome results
None listed