Short and middle term comparison of the effects of hypocaloric low carbohydrate diet versus Mediterranean diet on endothelial function measured by means of flow mediated dilation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN53451414

Enrollment

Registered

2007-04-13

Start date

2006-10-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity Nutritional, Metabolic, Endocrine Obesity

Interventions

Group one: hypocaloric low carbohydrate diet for two months Group two: hypocaloric Mediterranean diet for two months

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Female subjects 2. Range of age 30 to 50 years 3. Range of Body Mass Index (BMI) from 27 kg/m^2 to 39.9 kg/m^2 4. Non-diabetic, non-hypertensive, non-dislipidemic subjects

Exclusion criteria

Exclusion criteria: 1. Any metabolic, cardiovascular or systemic disease 2. Any drug treatment

Design outcomes

Primary

Measure	Time frame
Short (five to seven days) and middle (two months) modifications of flow mediated dilation. These will be measured three times: 1. Before starting the diet treatment 2. Five to seven days after starting the diet treatment 3. Two months after starting the diet treatment	—

Secondary

Measure	Time frame
1. Traditional anthropometric, metabolic and cardiovascular risk factors 2. Intra-renal haemodinamic measurements (resistance and pulsatility indexes) These will be measured three times: 1. Before starting the diet treatment 2. Five to seven days after starting the diet treatment 3. Two months after starting the diet treatment	—

Countries

Italy

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026