Depression Mental and Behavioural Disorders Depressive episode
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 24 depressed NHS patients, aged 18 - 65 years, will be recruited from routine referrals to the Newcastle CBT Centre (NCBTC) and secondary care mental health services within the 3Ns Trust. Inclusion criteria: 1. Adults aged 18 - 65 years 2. Major depressive episode as the primary diagnosis, first or second major episode, lasting at least 12 months duration 3. Moderate or severe depression symptoms 4. Treatment-resistance to at least one course of anti-depressant previously administered at an adequate dose for adequate period, treatment resistance to other primary care interventions
Exclusion criteria
Exclusion criteria: 1. Previous individual or group CBT following a recognised protocol within secondary care services 2. Three or more major episodes of depression 3. People with bi-polar disorder, psychosis, learning disability, borderline personality disorder, alcohol or addiction problems
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. CORE 2. Hamilton Depression Scale (HAM-D) 3. Beck Depression Inventory (BDI) 4. Beck Hopelessness Scale (BHS) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Quality of Life and Social Functioning: to be determined through discussion with Psychological Therapies Research Network 2. Mediating Variables: Dysfunctional Attitudes Scale (DAS), Automatic Thoughts Questionnaire (ATQ), Sentence Completion Test for Depression (SCD), Roles and Goals Questionnaire (RAG). | — |
Countries
United Kingdom