Evaluation of the immune system in older adults that receive a nutritional complement enriched with beta glucans extracted from the fungus Ganoderma lucidum

Evaluation of changes in T cells subpopulations and NK (natural killer) cells in older adults during a 12 week intervention with a nutritional complement enriched with biotechnologically Ganoderma lucidum extracted beta glucans

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN53126301

Enrollment

Registered

2015-05-22

Start date

2014-12-16

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Improvement in the baseline levels of immune system components in older adults. Not Applicable

Interventions

Participants receive a nutritional supplement in a maltodextrin and polydextrose matrix, enriched with beta glucans extracted biotechnologically from Ganoderma lucidum for a 12 week period.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adults aged 65-85 attached to the Elderly Welfare Center, San Bernardo - Berta Arias Foundation, Botero (FUNDARIAS) (Centro de Bienestar al Anciano San Bernardo, Fundación Berta Arias de Botero (FUNDARIAS)).

Exclusion criteria

Exclusion criteria: 1. Refuse to sign and acept the informed consent 2. Not within the General and Social Health Care System of Colombia 3. Use of corticosteroids or any other medical or pharmaceutical intervention 4. Anticoagulant treatment, stent, valve replacement, history of stroke 5. Diabetes 6. Mental impairments 7. Malnutrition or malnutrition risk

Design outcomes

Primary

Measure	Time frame
Measured in blood sample at baseline then 12 weeks after intervention: 1. CD4+ and CD8+ T lymphocytes counts, measured by flow cytometry in whole blood collected 2. NK cells counts, measured by flow cytometry (CD16+/CD56+)	—

Secondary

Measure	Time frame
1. Haemoleucogram measured by flow cytometry 2. Serum IgA measured by immunoturbidimetry 3. Lipid profile measure by enzymatic colorimetric assay 4. Glucose levels measured by ultraviolet test 5. Nutritional and anthropometric measurements: body mass index (BMI)	—

Countries

Colombia

Contacts

Public ContactSergio Urrego

surregor@progal-bt.com+54 4442060

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026