BeWEL: the impact of a bodyweight and physical activity intervention on adults at risk of developing colorectal adenomas

Conditions

Colorectal cancer and cardiovascular disease Cancer Colorectal cancer

Annie S. Anderson, Angela M. Craigie, Stephen Caswell, Shaun Treweek, Martine Stead et al. (16 authors)

BMJ2014-03-07116 citations

Meeting the challenges of recruitment to multicentre, community-based, lifestyle-change trials: a case study of the BeWEL trial.

Treweek S, Wilkie E, Craigie AM, Caswell S, Thompson J, Steele RJ, Stead M, Anderson AS, BeWEL team.

2013-12-1819 citations

10.1186/1745-6215-14-436

Detailed protocol for the lifestyle intervention in the BeWEL randomised controlled trial of weight loss in adults who have had a colorectal adenoma.

Caswell S, Craigie AM, Wardle J, Stead M, Anderson A.

2012-05-257 citations

10.1136/bmjopen-2012-001276

Study protocol for BeWEL: the impact of a BodyWEight and physicaL activity intervention on adults at risk of developing colorectal adenomas.

Craigie AM, Caswell S, Paterson C, Treweek S, Belch JJ, Daly F, Rodger J, Thompson J, Kirk A, Ludbrook A, Stead M, Wardle J, Steele RJ, Anderson AS.

2011-03-2524 citations

10.1186/1471-2458-11-184

Interventions

Intervention group (IG): Receives the "BeWEL" personalised intervention programme, personal body weight scales and invitations to undertake supervised monthly body weight recordings. T

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 50 to 74 years, either sex 2. Have participated in the NHS Scottish Bowel Screening Programme 3. Had one or more benign adenomas removed 4. Body mass index (BMI) greater than 25 m/kg2 5. Physically able to undertake exercise requirements 6. Able to provide informed consent

Exclusion criteria

Exclusion criteria: 1. Normal colonoscopy 2. Diagnosed with cancer as a result of their colonoscopy 3. Currently suffering from cancer at another site 4. Rely on insulin administration for glucose control 5. BMI less than 25 kg/m2

Design outcomes

Primary

Measure	Time frame
Current primary outcome measures as of 24/05/2011: Measured at baseline, 3 months and 12 months: Body weight (BMI) Previous primary outcome measures: Measured at baseline, 3 months and 12 months: 1. Body weight (BMI) 2. Waist circumference	—

Secondary

Measure	Time frame
Measured at baseline, 3 months and 12 months: 1. Waist circumference (Added 24/05/2011) 2. Lipid profile 3. Homeostatic model assessment (HOMA) from fasting insulin and glucose 4. HbA1C 5. Blood pressure 6. Diet 7. Self-assessed health and self-efficacy 8. Objectively measured physical activity levels (from 7 day SenseWear physical activity monitor) 9. Change in primary outcome measures by deprivation 10. Perceived acceptability of the programme (from post-study questionnaires and interviews) 11. Intervention costs	—

Measure

Time frame

Measured at baseline, 3 months and 12 months: 1. Waist circumference (Added 24/05/2011) 2. Lipid profile 3. Homeostatic model assessment (HOMA) from fasting insulin and glucose 4. HbA1C 5. Blood pressure 6. Diet 7. Self-assessed health and self-efficacy 8. Objectively measured physical activity levels (from 7 day SenseWear physical activity monitor) 9. Change in primary outcome measures by deprivation 10. Perceived acceptability of the programme (from post-study questionnaires and interviews) 11. Intervention costs

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Countries

Scotland, United Kingdom

Outcome results

None listed