WEight Loss in Learning Disabilities and Obesity (WELLDO): A weight loss intervention for adults with learning disabilities and obesity

A single-blind, randomised controlled trial of a weight loss intervention for adults with learning disabilities and obesity

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN52903778

Enrollment

Registered

2014-03-12

Start date

2014-02-01

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity Nutritional, Metabolic, Endocrine Obesity

Interventions

After collection of baseline data, participants will be randomly allocated to one of the two study groups: TAKE 5 or Waist Winners Too. Individuals recruited may live together and/or be supported by t

gradually increasing physical activity levels to the recommended 30 minutes of accumulated physical activity, at least five days per week

reducing sedentary behaviours to less than four hours per day on average. To achieve these aims behavioural principles are incorporated into the intervention including motivational interviewing, self-

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. A learning disability 2. Over 18 years old (there is no upper age limit) 3. Body mass index (BMI) greater than or equal to 30 kg/m2 4. Able to walk independently 5. Not currently on a prescribed or restricted diet e.g. for phenylketonuria or diabetes 6. No intentional weight loss over the previous 3 months

Exclusion criteria

Exclusion criteria: 1. Individuals with genetic syndromes, Prader Willi syndrome, Cohen syndrome or Bardet- Biedl syndrome (need a specific program to support weight loss) 2. Currently taking part in another research study 3. Pregnant 4. Taking medication prescribed for the purpose of weight loss or over the counter medication designed for weight loss

Design outcomes

Primary

Measure	Time frame
Body weight is measured using data collected at baseline, 6 months post randomisation and 12 months post randomisation	—

Secondary

Measure	Time frame
1. Weight loss of 5% or more of initial body weight (Yes/No) 2. Change in BMI 3. Change in waist circumference 4. Change in percentage body fat 5. Mean percentage time per day spent engaged in moderate/vigorous intensity physical activity, measured by accelerometers 6. Mean percentage time per day spent engaged in light intensity physical activity, measured by accelerometers 7. Mean percentage time per day spent engaged in sedentary behaviour, measured by accelerometers 8. Quality of life as measured by the EQ-5D Data will be collected at baseline, 6 months post randomisation and 12 months post randomisation.	—

Measure

Time frame

1. Weight loss of 5% or more of initial body weight (Yes/No) 2. Change in BMI 3. Change in waist circumference 4. Change in percentage body fat 5. Mean percentage time per day spent engaged in moderate/vigorous intensity physical activity, measured by accelerometers 6. Mean percentage time per day spent engaged in light intensity physical activity, measured by accelerometers 7. Mean percentage time per day spent engaged in sedentary behaviour, measured by accelerometers 8. Quality of life as measured by the EQ-5D Data will be collected at baseline, 6 months post randomisation and 12 months post randomisation.

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Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 5, 2026